Industry: Healthcare | Publish Date: 24-Aug-2023 | No of Pages: 93 | No. of Tables: 83 | No. of Figures: 32 | Format: PDF | Report Code : N/A
The Germany Early Toxicity Testing Market was valued at USD 246.68 million in the year 2022 and is predicted to reach USD 422.28 million by 2030, with a CAGR of 5.95% from 2023 to 2030. Early toxicity testing is a fundamental procedure aimed at assessing the potential toxicity or adverse effects of drugs, chemicals, or various substances during their preliminary developmental stages. Typically conducted in vitro or through animal models, this evaluation occurs prior to any human testing.
The overarching objective of early toxicity testing is to swiftly uncover any safety-related apprehensions linked to a substance, thus facilitating informed decisions about its feasibility for continued development and subsequent testing. By undertaking early toxicity testing, the risks of adverse effects on both human subjects and animals during clinical trials are mitigated, simultaneously curtailing expenses and time invested in the overall drug development trajectory. This intricate process encompasses a gamut of examinations and assays, encompassing cell viability assessments, genotoxicity evaluations, and pharmacokinetic investigations.
The specific modalities employed are contingent on the intrinsic nature of the substance under scrutiny and its intended application. Recognized as an indispensable phase within the drug development journey, early toxicity testing profoundly bolsters the assurance of safety and efficacy for novel drugs and other substances prior to their regulatory endorsement for human utilization.
Germany is home to several large pharmaceutical companies developing innovative testing methods to conduct extensive toxicity testing on their products to improve safety and efficacy of their products before they can be approved for use. For instance, in February 2023, Evotec AG launched its first innovation center for fragment-based drug discovery, namely EvoFIND. The center is expected to focus on developing new technologies and tools for fragment-based drug discovery to improve efficiency and accuracy of toxicity testing by identifying potential toxicities early in the drug development process.
The presence of strong medical infrastructure and increased public health awareness as a result of an educated populace propels the growth of the germany early toxicity testing market. According to the International Trade Administration, Germany is the 3rd largest medical technology market in the world and the largest in Europe, with a value of USD 35.8 billion, which is equal to 25.6% of the Europe market.
In addition, Evotec AG collaborated with Novartis for a three-year drug discovery collaboration to develop small molecule therapies for multiple indications, including cancer and neurological disorders with optimal safety profiles and high efficacy. The collaboration is expected to accelerate the development of new therapies while contributing to advancements of the early toxicity testing methods and technologies.
Stringent regulations set by regulatory bodies such as the US FDA and the EMA require extensive and rigorous testing for drug development and safety, which can be time-consuming and expensive and restrain the growth of the German early toxicity testing market. The complexity and cost of complying with these regulations can pose a significant challenge for small and medium-sized companies that may not have the resources to carry out extensive testing.
As a result, some companies may choose to delay or abandon drug development projects, which can limit demand for early toxicity testing services. Moreover, stringent regulations can also result in a lengthy approval process for new drugs, further delaying the time it takes for drugs to reach the market. This, in turn, is expected to hamper the growth of the market.
The introduction of new technologies such as in-vitro modeling using 3D cell culture is expected to provide new lucrative opportunities for the early toxicity testing market in Germany, during the forecast period. Use of 3D cell cultures can better mimic complexity of tissues and organs, providing more accurate and reliable results for toxicity testing. Traditional 2D cell culture models are limited in their ability to mimic complexity of human tissues and organs, often leading to inaccurate and unreliable results in toxicity testing.
However, the use of 3D cell culture models can better mimic structural and functional complexity of tissues and organs, providing more accurate and reliable results for toxicity testing. 3D cell cultures allow growth and interaction of multiple cell types, creating a microenvironment that more closely resembles human tissues and organs. This can better predict toxic effects of drugs and chemicals in the human body, reducing the risk of adverse effects in clinical trials. Hence, such factors propel the market growth.
The Germany Early Toxicity Testing industry includes several market players such as Inotiv Inc., Bio-Rad Laboratories Inc., Evotec A.G., Agilent Technologies Inc., Wuxi Apptec, Bruker, Perkinelmer Inc., Enzo Biochem Inc., Danaher Corporation, Eurofins Scientific SE, Charles River Laboratories International, Inc., Labcorp Drug Development., Promega Corporation, Insphero AG., and Thermo Fisher Scientific Inc.
The Germany Early Toxicity Testing market report provides a quantitative analysis of the current market estimations throughout 2023-2030 that assists in identifying the prevailing market opportunities to capitalize on.
The study comprises a deep-dive analysis of the current and future German early toxicity market trends to depict the prevalent investment pockets in the market.
The information related to the key drivers, restraints, and opportunities and their impact on the market is provided in the report.
The competitive analysis of the key players along with their market share in the Germany Early Toxicity Testing industry, is mentioned.
The SWOT analysis and Porter’s Five Forces model are elaborated in the study.
Value chain analysis in the market study provides a clear picture of the stakeholders’ roles.
In Vivo
In Vitro
Cell Culture
PCR
ELISA
Western Blotting
Protein Binding Assays
In Silico
Genotoxicity
Dermal Toxicity
Skin Toxicity
Ocular Toxicity
Phototoxicity
Others
Pharmaceutical Industry
Cosmetic Industry
Chemical Industry
Food Industry
Others
REPORT SCOPE AND SEGMENTATION:
Parameters |
Details |
Market Size in 2022 |
USD 246.68 Million |
Revenue Forecast in 2030 |
USD 422.28 Million |
Growth Rate |
CAGR of 5.95% from 2023 to 2030 |
Analysis Period |
2022–2030 |
Base Year Considered |
2022 |
Forecast Period |
2023–2030 |
Market Size Estimation |
Million (USD) |
Growth Factors |
Innovative methods in pharmaceutical companies.
Strong healthcare infrastructure. |
Companies Profiled |
15 |
Market Share |
Available for 15 companies |
Customization Scope |
Free customization (equivalent up to 80 working hours of analysts) after purchase. Addition or alteration to country, regional, and segment scope. |
Pricing and Purchase Options |
Avail customized purchase options to meet your exact research needs. |
Inotiv Inc.
Bio-Rad Laboratories Inc
Evotec A.G.
Agilent Technologies Inc
Wuxi Apptec
Bruker
Perkinelmer Inc.
Enzo Biochem Inc.
Danaher Corporation
Eurofins Scientific SE
Charles River Laboratories International, Inc.
Labcorp Drug Development.
Promega Corporation
Insphero AG
Thermo Fisher Scientific Inc.